ACTH 11-24 ( Adrenocorticotropic Hormone (11-24) )

Catalog No. M29947 CAS No. 4237-93-8

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Product Name

ACTH 11-24
Note

Research use only, not for human use.
Brief Description

ACTH (11-24) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells.
Description

ACTH (11-24) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells.(In Vitro):ACTH (11-24) acts as an antagonist of adrenocorticotropic hormone receptor. ACTH (11-24) induces cortisol secretion submaximally in freshly dispersed or cultured beef adrenal cortical cells. The maximal cortisol release by ACTH (11-24) is enhanced by forskolin but inhibited by calcium channel blockers.(In Vivo):ACTH (11-24) blocks electroacupuncture (EA) anti-edema but not EA anti-hyperalgesia in rats.
Synonyms

Adrenocorticotropic Hormone (11-24)
Pathway

Others
Target

Other Targets
Recptor

Adrenocorticotropic hormone receptor
Research Area

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Indication

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Li ZG, et al. Adrenocorticotropin(1-10) and -(11-24) promote adrenal steroidogenesis by different mechanisms. Endocrinology. 1989 Aug;125(2):592-6.

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